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January 8 |
Introductory confusion! (Nothing works as planned) Mammal eggs. |
| [first part of lecture only, 29 minutes] |
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January 10 |
Sea urchin embryos compared with vertebrate embryos |
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January 13 |
The branching pathway of embryonic cell differentiation |
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January 15 |
Curvature, Tensions and Pressures create geometry; P=T*C
|
| part 1 [first 12 minutes] |
| part 2 [rest of lecture, after a brief camera problem] |
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January 17 |
Symmetry of causes equals symmetry of structures. (Plus Emmy Noether) |
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January 22 |
Epithelial folding; Turing's Reaction-Diffusion mechanism |
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January 24 |
Cell-sorting & forces creating anatomy |
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January 27 |
Organ formation using rat-flavored jello |
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February 3 |
Nervous system, notochord, mesoderm; our theory of tendons |
| part 1 [first 30 minutes] |
| part 2 [last 15 minutes] |
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February 5 |
Tendons, arteries, somites, myotomes, kidneys & heart |
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February 7 |
How computer simulations help understand chemotaxis
|
| chemotaxis video before the lecture [music: Ralph Vaughan-Williams, The Wasps] |
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| more computer simulations: |
| Chemotaxis part one; smaller (.mp4) version |
| Chemotaxis part two; smaller (.mp4) version |
| Turing mechanism |
| Drawing a graph of changes in curvature |
| Simulation of shape changes |
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February 10 |
Tooth and gland formation (home-made animations) |
| part 1 [27 minutes] |
| part 2 [22 minutes] |
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February 12 |
Cellular slime molds; "regulation" of relative sizes of parts |
| teleost egg animation shown at the end of the lecture |
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February 17 |
Monozygotic twins; sharing of amnions & chorions; Roux experiment |
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February 19 |
Ride of the Wagnerian Valkyrie Slugs; review for the next hour exam |
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February 24 |
Prevention of polyspermy |
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February 26 |
Ectoderm, and organs that develop from ectoderm |
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February 28 |
Nerve axon guidance. Retina-brain connection; ephrins |
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March 3 |
Dog noses; hairs, papillae; More about ectoderm; some birth defects |
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March 5 |
Plant Developmental Biology; auxin, and discovery by bioassays |
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March 7 |
Embryonic induction (rainy day, when few students attended) |
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March 17 |
Bird teeth induction; "Primary Induction"; how bioassays can fail |
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March 19 |
Pattern formation; cellular automata; gradients & how they form |
| cellular automaton demonstration [music: Grieg, In the Hall of the Mountain King, from Peer Gynt] |
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March 21 |
Limb bud development; control of anteror-posterior & dorso-ventral axes |
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March 24 |
More about causation of axes; regeneration of legs |
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March 26 |
Limb buds; effects of retinoic acid; symmetry of patterns |
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March 28 |
Chromatin: A lecture by Taylor Penke [edited, with PowerPoint slides inserted]> |
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March 31 |
Mechanisms that mimic diffusion gradients, etc. |
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April 4 |
Sex determination |
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April 7 |
Metamorphosis |
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April 9 |
Aging |
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April 11 |
Regeneration; slides of "work of adhesion |
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April 14 |
Development of immunity |
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April 16 |
The many different abnormalities of cancer cells |
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April 21 |
Effects of converting normal cells to cancerous behavior |
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April 23 |
"Wisteria" poem. Evo-Devo (Evolutionary Developmental Biology) |
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April 25 |
Review; imagine how embryology could be different than it is |
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| back to syllabus |