web sites: http://www. albertkharris.com and http://www.bio.unc.edu/faculty/harris/
office phone 919-966-1230
Teaching assistants: Amanda Whitlock and Taylor Penke
Textbook: Optional; Either the 7th, 8th, 9th or 10th (newest) edition of Scott Gilbert's "Developmental Biology"
The Biology 441 lab is NOT required for students taking the lecture course. It is a separate 1-hour course.
Review questions & other material needed for exams will be on this course's web site. (No password needed)
|1) Wed. Jan 8||Mammal embryo development in contrast to other vertebrates; videos; tables showing comparisons|
|2) Fri. Jan 10||Comparisons between development in sea urchins, fish, frogs, birds; a figure to study|
|3) Mon. Jan 13||Subdivision of embryos into germ layers; further subdivision, differentiation; lecture notes: videos|
|4) Wed. Jan 15||What are the physical forces that build anatomical structures? Not "growth;" lecture notes|
|5) Fri. Jan 17||Symmetry: A key concept for explaining causation of shapes; lecture notes|
|Mon. Jan. 20||******* Holiday in honor of Martin Luther King ********|
|6) Wed. Jan. 22|| Curvature, stress and stiffness are tensors: quantities that vary with direction; forces that shape anatomical structures;
more on symmetry (also added to the symmetry page from Friday); more videos have also been added.
|7) Fri. Jan. 24||Sorting out by dissociated and randomly mixed cells; cell-cell adhesion proteins. lecture notes;
some things to think about (added February 9th)
|8) Mon. Jan. 27||Review for first exam: first set of review questions|
second set of review questions
third set of review questions
fourth set of review questions
outline and some additional notes on the topics to be covered on the exam
|9) Wed. Jan. 29||snow day|
|10) Fri. Jan. 31||first hour exam|
|11) Mon. Feb. 3||Mesoderm: notochord, somites, kidneys and male sex ducts; lecture notes;
Some additional information was added to the figures showing rows of somites on Feburary 9th, and two more figures were added on February 17th.
|12) Wed. Feb. 5||Lateral plate mesoderm: coelom cavity, heart, gonads, primordial germ cells.
The animations of blood vessel development shown in class and the birefringence videos have been added to the video collection
|13) Fri. Feb. 7||Endoderm: thyroid, salivary glands, stomach, intestines, liver, pancreas; lecture notes; another figure was added to this page March 4th.|
|14) Mon. Feb. 10||Stomodeum, teeth (see lecture notes for Feb. 7)|
|15) Wed. Feb. 12||Extraembryonic membranes and placenta; lecture notes
Some links to YouTube videos of embryonic development have also been added.
|16) Fri. Feb. 14||snow day|
|17) Mon. Feb. 17||Twinning, regulation lecture notes
The lecture on fertilization and mechanisms that minimize polyspermy will be deferred until after the next hour exam.
|18) Wed. Feb. 19||Review for second hour exam; review questions posted Feb 16th; more questions added February 18th.
February 20, 2 pm: Some videos showing computer simulations of chemotaxis have been added to the page with the video recordings of the lectures. If you're having trouble with this concept, these may help you study.
|19) Fri. Feb. 21||second hour exam|
|20) Mon. Feb. 24||Blocks to polyspermy lecture notes|
|21) Wed. Feb. 26||Ectoderm lecture notes;
the ephrin drawing and the video of axons from Friday's lecture were added to this page March 2, 7:15 pm
|22) Fri. Feb. 28||ectoderm, continued; see notes for Wednesday|
|23) Mon. Mar. 3||Guidance of the optic nerve to the brain: "neural projections"; feathers and hair; lecture notes|
|24) Wed. Mar. 5||Development of higher plants, in contrast to animals lecture notes|
|25) Fri. Mar. 7||Embryonic induction|
|26) Mon. Mar. 17||More on induction; bioassays, genetic screens, & other methods; lecture notes|
|27) Wed. Mar. 19||Gradients, and why embryology needs computer simulations lecture notes|
|28) Fri. Mar. 21||Limb bud development lecture notes|
|29) Mon. Mar. 24||Limb bud development, continued|
|instructions for this week's labs|
|30) Wed. Mar. 26||What do we most need to understand about cell differentiation?|
|31) Fri. Mar. 28||Guest Lecture: Taylor Penke, Chromatin; lecture notes; revised Sunday morning, figures have been added|
|32) Mon. Mar. 31||Review for third exam; review questions; the list is now complete.|
|33) Wed. Apr. 2||Third hour exam|
|34) Fri. Apr. 4||Sex determination; lecture notes|
|35) Mon. Apr. 7||Metamorphosis; lecture notes|
|36) Wed. Apr. 9||Aging as a developmental phenomenon; lecture notes|
|37) Fri. Apr. 11||Regeneration; lecture notes|
|38) Mon. Apr. 14||Immunology and Autoimmunity have Embryological Causes; lecture notes|
|39) Wed. Apr. 16||Cancer in relation to embryological cell growth; lecture notes|
|Good Friday Holiday|
|40) Mon. Apr. 21||Cancer, continued|
|41) Wed. Apr. 23||"Evo-Devo" = Evolutionary Developmental Biology; lecture notes|
|42) Fri. Apr. 25||Review of course; lecture notes|
|review questions for the last part of the course|
|office hours: every afternoon this week|