Biology 441   VERTEBRATE EMBRYOLOGY   Spring Semester 2011    Albert Harris

MWF 9-9:50 Wilson 107

Office Room 103 Wilson Hall:
Office Hours Mon 10:00-12:00, Friday 10:00-3:00
office phone 966-1230; home 493-1572

Teaching Assistants: Alicia Greenwalt:   and  Yuxiang Liu:


1) Mon. Jan 10 Mammal eggs differ in important ways. Ploidy at different stages; some special embryological words;
web page on regulation and ploidy
2) Wed. Jan 12 Comparison of gastrulation in urchins, amphibians & mammals; web page on gastrulation
3) Fri. Jan 14 Sea urchin early development
Mon. Jan 17 Holiday in Honor of Martin Luther King Jr. and the Civil Rights Movement
4) Wed. Jan 19 Germ layer subdivisions: How to build a body out of cells; web page; endoderm
5) Fri. Jan. 21 Embryology of the nervous system; web page
6) Mon. Jan. 24 Mesenchymal cells, and how their locomotion is controlled; reading assignment
7) Wed. Jan. 26 continued discussion of the assignment from Monday; contact inhibition diagram
8) Fri. Jan. 28 Epithelial sheets, how they change shapes and move; Bard chapter 6; web page
9) Mon. Jan 31 Extraembryonic membranes; web page
10) Wed. Feb 2 Fertilization, mechanisms of prevention of polyspermy; web page
11) Fri. Feb 4 Gastrulation in mammals, birds, fish, amphibians; Bard chapter 3; gastrulation; web page on fish embryology
12) Mon. Feb 7 Experimental embryology; regulation, induction, "scaling" and other concepts; Bard chapters one and two;
web page on regulative development
more text was added to this page on Wednesday morning
13) Wed. Feb 9 Fate mapping, regulative development compared with mosaic development
14) Fri. Feb 11 Review for first exam; review questions
15) Mon. Feb 14 First exam
16) Wed. Feb 16 How forces create shapes. The concept of tensors, curvature, tension, etc. web page;
new material was added Feb. 27.
17) Fri. Feb 18 More about cell and organ shape
18) Mon. Feb 21 Reaction-diffusion systems: Turing etc. web page
19) Wed. Feb 23 Symmetry as a unifying concept of anatomy and embryology web page;
new material was added Feb. 27.
20) Fri: Feb 25 Does Wilson's cell sorting discovery tell us how embryos develop? web page
21) Mon. Feb 28 Limb bud development
22) Wed. Mar 2 Limb bud development web page
23) Fri. Mar 4 Comparison of development of plants with animal embryology web page
  answer key to first exam
Mon. Mar 7 - Fri. Mar 11 spring vacation
24) Mon. Mar 14 Comparison of development of plants with animal embryology
25) Wed. Mar 16 Comparison of early insect development with vertebrate embryology; web page
26) Fri. Mar 18 Discovery of Hox genes, and how do Hox genes control vertebrate development;
pdf file on gap genes and colinearity
27) Mon. Mar 21 How to use genetics to discover how molecules control early development
28) Wed. Mar 23 More about molecular mechanisms of early development; web page
29) Fri. Mar 25 Review for second examination. review material.
30) Mon. Mar 28 Second exam
  answer key to second exam
31) Wed. Mar 30 Comparison of heart and kidney development; web page
32) Fri. Apr 1 Programmed cell death = apoptosis. How does it work; how do embryos use it? web page
33) Mon. Apr 4 Guidance of optic nerve fibers from the eye to the brain; neural connections (see Jan. 21 web page)
34) Wed. Apr 6 More about nerve fiber guidance
35) Fri. Apr 8 Birth defects in relation to normal development
36) Mon. Apr 11 Organ regeneration; web page
37) Wed. Apr 13 Metamorphosis
38) Fri. Apr 15 Jonathan Bard's 37 questions, on pages 277 and 278; web page
39) Mon. Apr 18 Embryonic development of the immune system (not "recognizing" "self")
40) Wed. Apr 20 More about development of the immune system; web page
Fri. Apr 22 Good Friday Holiday
41) Mon. Apr 25 Cancer, and cell invasiveness in relation to normal development; web page
42) Wed. Apr 27 last class: Cancer, and cell invasiveness in relation to normal development
  review material for final exam.
More questions were added Sunday at 5 pm. This completes the list.
Friday, May 6, 8:00 am Final Exam



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