web sites: http://www. albertkharris.com and http://www.bio.unc.edu/faculty/harris/
office phone 919-966-1230
Teaching assistants: John Noto and Diego Hipolito Canario
Optional textbook: Human Embryology and Developmental Biology, by Bruce M. Carlson. Any edition is OK.
The Biology 441 lab is NOT required for students taking the lecture course. It is a separate 1-hour course.
Labs will begin on January 18-19. lab syllabus
exams and grading
Lecture notes, videos, review questions, and other material needed for exams will be posted on this web site throughout the semester.
Please check it frequently for updates.
links to web pages for the preceding ten years, including sample exam questions: "review questions"
|1) Wed. Jan 11||
Mammal Embryology in Contrast with Sea Urchin Embryology
|2) Friday Jan 13||
Subdivision of Vertebrate Embryos Into Ectoderm, Mesoderm & Endoderm
|Monday Jan 16||******* Holiday in Honor of Martin Luther King Jr. ********|
|3) Wednesday Jan 18||
Embryology of Teleost Fish. Why are zebra-fish good "model organisms?
|4) Friday Jan 20||
Embryology of Amphibians (Salamanders & Frogs). Advantages for Experiments
|5) Monday Jan 23||
Embryonic Development of Birds, Reptiles & Mammals. Why so similar?
|6) Wednesday Jan 25||
Experimental Embryology, Regulation, Fate maps, In Situ Labeling
some vocabulary to review
illustrations shown in class
|7) Friday Jan 27||Experimental Embryology, continued (see notes for Wednesday)|
A video of plutei (larvae of sea urchins) was shown before the lecture, accompanied by a recording of the
|8) Monday Jan 30||
Cell Sorting and Discovery of Selective Adhesion Proteins
preparing for the first hour exam
|9) Wednesday Feb 1||
Cell Sorting, continued lecture notes
|10) Friday Feb 3||
Review for first examination
review questions (posted Tuesday 10:15 pm)
|11) Monday Feb 6||First Examination|
|12) Wednesday Feb 8||
Easy Mathematics about Surface Curvatures, Tensions and Pressures
video (with narration), showing a simple computer program to graph curvature
|13) Friday Feb 10||
How Do Physical Forces Cause the Shapes of Anatomical Structures?
(lecture notes continued from February 8th)
Animations shown at the beginning of the lecture:
|14) Monday Feb 13||
Symmetries of Causes Control Symmetries of Anatomical Shapes
|15) Wednesday Feb 15||
Reaction-Diffusion Systems: How Instabilities Create Geometric Patterns|
some thought questions about curvature and symmetry
|some web links to look at about various topics in embryology
added Thursday Feb 16 at 10:45 am; revised Friday Feb 17 at 12:45 pm
|16) Friday Feb 17||Fractals and Branching Structures. lecture notes
Somites and the Notochord. This topic will be continued on Monday; lecture notes will be posted then.
Some video links from the web. Please look at the ones on somites.
Optional reading that you might find interesting (posted Sunday at 3 pm)
|17) Monday Feb 20||
Pattern Formation; then Somites and Other Structures from Mesoderm, continued |
lecture notes on patterns
lecture notes on mesoderm
links to the videos shown in class
|18) Wednesday Feb 22||
Review for Second Examination
Please note: You are also responsible for the figures and illustrations posted on the course
The question list was edited at 4:10 pm on Tuesday. Some hints were added, and some questions that dealt with material that hasn't been fully covered yet were flagged with **. As before, questions marked with an * are more difficult and not many will be asked.
|19) Friday Feb 24||Second Examination|
|20) Monday Feb 27||
Ovaries and Testis; Primordial Germ Cells and Gamete Formation; Heart.
See notes on mesoderm from February 20 - the picture of primordial germ cells has been added.
Pascal program simulating the Liesegang reaction, shown at the beginning of the lecture
|21) Wednesday Mar 1||
Cartilage and Bone
|22) Friday Mar 3||
notes on retino-tectal projections were added March 8, 7:45 am
|23) Monday Mar 6||
Chemotaxis, and more on ectoderm
lecture notes and video links on chemotaxis
This page was revised on April 3. New illustrations were added.
|24) Wednesday Mar 8||
Retino-Tectal Projections (continuation of Ectoderm)
see lecture notes from March 3
|25) Friday Mar 10||Endoderm lecture notes|
|March 13-17 spring break|
|26) Monday Mar 20||
Development of higher plants, in contrast to animals
lecture notes [updated Tuesday 11 am]
|27) Wednesday Mar 22||
Bioassays; lecture notes
Sex Determination; lecture notes
|28) Friday Mar 24||Limb buds; lecture notes|
|29) Monday Mar 27||Limb buds, continued|
|30) Wednesday Mar 29||
Review for third examination
first set of review questions
second set of review questions
third set of review questions
|31) Friday Mar 31||Third Examination|
|32) Monday Apr 3||Regeneration, Especially of Salamander Limbs; lecture notes|
|33) Wednesday Apr 5||
Regeneration, continued; lecture notes;
Atherosclerosis; lecture notes
|34) Friday Apr 7||Metamorphosis; lecture notes|
|35) Monday Apr 10||
Immunology, Allergies, and Autoimmune Diseases in Relation to Embryology
These notes were revised April 12 at 1:30 pm.
|36) Wednesday Apr 12||Immunology, continued|
|Friday April 14||******* Holiday ********|
|37) Monday Apr 17||
Locomotion of Amoebae and Tissue Cells
|38) Wednesday Apr 19||
Cell Locomotion and Traction, continued
See lecture notes from April 17, which were modified on April 19 at 2:00 PM.
|39) Friday Apr 21||Cancer as Disruption in Embryological Mechanisms; lecture notes|
|40) Monday Apr 24||Aging lecture notes|
|41) Wednesday Apr 26||
Guest lecture by teaching assistant John Noto:
Embryonic Development in Fruit Flies
downloadable PowerPoint file
|42) Friday Apr 28||
Evo-Devo: lecture notes|
Course Review: lecture notes
Dr. Harris will be in his office or in the lecture room all day on
Wednesday, May 3, beginning at 9:00, for exam review and questions.
|FINAL EXAM: Monday, May 8, 8:00 am|