web sites: http://www. albertkharris.com and http://www.bio.unc.edu/faculty/harris/
office phone 919-966-1230
Teaching assistants: Amanda Whitlock and Lyndsay Ratliff
Textbook: Langman's Medical Embryology, by Thomas W. Sadler
The Biology 441 lab is NOT required for students taking the lecture course. It is a separate 1-hour course.
Biology 441 labs will begin on January 14.
Links to lecture notes, videos, review questions, and other material needed for exams, will be added as the semester progresses.
links to web pages for the preceding ten years,
including sample exam questions: "review questions"
How the course will be graded
|1) Wed. Jan 7||Differences and similarities between human embryos versus sea urchin embryos; lecture notes and review questions|
|2) Fri. Jan 9||Subdivision of embryos into germ layers; lecture notes; review questions|
|3) Mon. Jan 12||Embryonic development in teleost fish; lecture notes; review questions|
|4) Wed. Jan 14||Class canceled because of weather|
|5) Fri. Jan 16||
Embryonic development of amphibians (= salamanders and frogs); lecture notes;
review questions on cell movements and induction
|Mon. Jan 19||******* Holiday in honor of Martin Luther King ********|
|6) Wed. Jan 21||Embryonic development of birds and reptiles; lecture notes and review questions;|
|7) Fri. Jan 23||Changes in strengths and directions of forces cause changes in shapes of cells, embryos and organs;
|8) Mon. Jan 26||Birth defects in relation to embryonic development; lecture notes; review questions
a few more notes on twins
|9) Wed. Jan 28||Review for first hour exam:
important vocabulary review
|10) Fri. Jan 30||First Hour Examination|
|11) Mon. Feb 2||Experimental Embryology, fate maps, the mystery of embryonic regulation; lecture notes|
|12) Wed. Feb 4||What physical forces build anatomical structures? Pressures & cytoplasmic contraction; lecture notes|
|13) Fri. Feb 6||How forces create specific shapes; Tensors; Pressure = Tension x Curvature|
|14) Mon. Feb 9||Different kinds of amoeboid locomotion; How cells crawl using cytoplasmic actin assembly; lecture notes|
|15) Wed. Feb 11||Reaction-diffusion systems for generating anatomical patterns|
|16) Fri. Feb 13||Reaction-diffusion systems, continued; lecture notes|
|17) Mon. Feb 16||Symmetry explains more than most people; lecture notes|
|18) Wed. Feb 18||snow day|
|19) Fri. Feb 20||more on symmetry and pattern formation; review questions
some personal reflections on symmetry
|20) Mon. Feb 23||Stem cells, and then ectodermal organs; notes on stem cells; and notes on ectodermal organs|
|21) Wed. Feb 25||snow day;
some review questions for the exam next week
review questions mostly on the Feb 2 lecture
review questions for the Feb 4 lecture
review questions for the Feb 13 lecture
review questions on ectodermal organs
|22) Fri. Feb 27||another snow day|
|23) Mon. Mar 2||continuing with ectoderm, and review for the exam|
|24) Wed. Mar 4||Second hour examination|
|25) Fri. Mar 6||Plant development, compared with animal embryology; lecture notes|
This lecture was cancelled because of weather.
Please watch last year's video on the same topic.
|26) Mon. Mar 16||Mesodermal organs; lecture notes|
|27) Wed. Mar 18||Mesodermal organs continued: heart (see Monday's notes)|
|28) Fri. Mar 20||Endodermal organs; lecture notes|
|29) Mon. Mar 23||Snakes! and prepatterns, positional information, shape homeostasis, and more
|30) Wed. Mar 25||Atherosclerosis; (lecture notes)|
|31) Fri. Mar 27||Limb buds; lecture notes|
|32) Mon. Mar 30||More on diffusion gradients and limb bud grafting; lecture notes;
two figures about limb grafting that were shown in this lecture
|33) Wed. Apr 1||Regeneration and apoptosis; lecture notes|
|Good Friday Holiday|
first set of review questions for the exam Monday 5 pm: Answers to the germ layer questions have been added.
second set of review questions
third set of review questions
fourth set of review questions
fifth set of review questions
This completes the list of review questions.
Remember that you are also responsible for all photographs and diagrams in the lecture notes.
|34) Mon. Apr 6||Regeneration continued, and review for the exam|
|35) Wed. Apr 8||Third hour examination|
|36) Fri. Apr 10||Sex determination: sometimes specific genes; ratios of chromosomes; or temperatures; lecture notes|
|37) Mon. Apr 13||Metamorphosis: Tadpoles to frogs; Caterpillars to butterflies? Plutei to urchins? lecture notes|
|38) Wed. Apr 15||Aging; lecture notes
Five common misunderstandings
|39) Fri. Apr 17||Immunology and Autoimmunity; lecture notes; figures were added Friday 10:25 am|
|40) Mon. Apr 20||Cancer lecture notes; revised 10:30 pm April 21|
|41) Wed. Apr 22||Cancer continued|
|42) Fri. Apr 24||Evo-Devo; lecture notes|
first set of review questions for the final exam
second set of review questions, and some more notes
third set of review questions
fourth set of review questions; one more question was added at 8:40 am on Friday.
|FINAL EXAM: Monday May 4, at 8 AM|