web sites: http://www. albertkharris.com and http://www.bio.unc.edu/faculty/harris/
office phone 919-966-1230
Teaching assistants: Becky Bigler and Claire Karasek
Textbook: Human Embryology and Developmental Biology, by Bruce M. Carlson. Any edition is OK.
The Biology 441 lab is NOT required for students taking the lecture course. It is a separate 1-hour course.
Syllabus for the lab [revised February 25]
Lecture notes, videos, review questions, and other material needed for exams will be posted on the web, linked to this syllabus page
(No password is required, and Sakai will not be used.)
exams and grading
|1) Mon. Jan 11||
Mammal Embryology in Contrast with Sea Urchin Embryology.
See 2016_videos.html for the videos of mammalian and sea urchin early divisions.
|2) Wed. Jan 13||
Subdivision of Embryos Into Ectoderm, Mesoderm & Endoderm
|3) Fri. Jan 15||
Embryology of Teleost Fish. Why are zebra-fish good "model organisms?;
|Mon. Jan 18||******* Holiday in Honor of Martin Luther King Jr. ********|
|4) Wed. Jan 20||
Embryology of Amphibians (salamanders & frogs). Advantages for Experiments;
slides and links to videos.
|5) Fri. Jan 22||Snow day. Should have been Embryonic Development of Birds, Reptiles & Mammals. Why so similar?|
|6) Mon. Jan 25||Snow day. Should have been Experimental Embryology, Regulation, Fate maps, In Situ Labeling|
|7) Wed. Jan 27||
Catch-up lecture: morphogenetic movements, twinning, and some other topics.
|8) Fri. Jan 29||Experimental Embryology; lecture notes; some additional information about Dictyostelium was added to these notes Tuesday afternoon.|
|9) Mon. Feb. 1||Pattern Formation in Embryonic Development; lecture notes|
revised review questions|
Don't panic: many of these questions are similar to ones that appeared in the earlier lists.
|10) Wed. Feb. 3||Review for first examination|
|11) Fri. Feb. 5||First Examination|
|12) Mon. Feb 8||
Easy Mathematics about Surface Curvatures, Tensions and Pressures; lecture notes;
video discussed but not shown in class
|13) Wed. Feb 10||continuation of Monday's topics|
|14) Fri. Feb 12||Symmetries of Causes Control Symmetries of Anatomical Shapes; lecture notes|
|15) Mon. Feb 15||snow day|
|16) Wed. Feb 17||
More on symmetry, then start Reaction-Diffusion Systems: How Instabilities Create Geometric Patterns
see 2016_videos.html for the cellular automata videos shown in class
|17) Fri. Feb 19||Reaction-Diffusion Systems: Turing, and Liesegang Rings; lecture notes. updated Sunday 1:20 pm|
|18) Mon. Feb 22||
Locomotion of Amoebae and Body Cells; lecture notes
new material has been added for Wednesday's lecture
|19) Wed. Feb 24||Review for Second Examination|
first set of review questions|
YOU CAN ALSO LOOK AT THE SAMPLE QUESTIONS FROM PAST YEAR'S LISTS, AND SEE HOW MANY OF THOSE YOU KNOW THE ANSWERS TO.
|20) Fri. Feb 26||Second Examination|
|21) Mon. Feb 29||
Mesoderm Development, somite formation; lecture notes;
links to some videos about somite formation; also see chapters 5 and 6 in the textbook
|22) Wed. Mar 2||Mesoderm continued: kidney and heart; see notes for Monday's lecture|
|23) Fri. Mar 4||Cartilage and bone; lecture notes|
|24) Mon. Mar 7||Ectoderm; lecture notes|
|25) Wed. Mar 9||Ectoderm, continued|
|26) Fri. Mar 11||Eye-Brain Connection, and Other Neural Projections; lecture notes|
|27) Mon. Mar 21||
Some more on Chemotaxis:
|28) Wed. Mar 23||Extra-embryonic Membranes; lecture notes; a new illustration was added March 29th, 1:45 pm|
|Fri. Mar 25||GOOD FRIDAY HOLIDAY|
|29) Mon. Mar 28||Finish Endoderm; see notes for March 21|
|30) Wed. Mar 30||Review for third examination|
|31) Fri. Apr 1||Third Examination|
|32) Mon. Apr 4||Electrical phenomena: blocks to polyspermy, galvanotaxis;lecture notes
fertilization in a sea urchin video of cells aligning in a voltage gradient
|33) Wed. Apr 6||Limb buds; please read Chapter 10 in the textbook; lecture notes|
|34) Fri. Apr 8||
Regeneration, Especially of Salamander Limbs; lecture notes
some notes on arteries
|35) Mon. Apr 11||Sex Determination (In Mammals, in Comparison with Reptiles, Flies, Bees); lecture notes|
|36) Wed. Apr 13||Metamorphosis (Especially in Amphibians in Comparison with Insects) lecture notes|
|37) Fri. Apr 15||Aging in Relation to Development; lecture notes|
Labs are now over for the semester.|
|38) Mon. Apr 18||
Autoimmune Diseases as Failure of the Tolerance Mechanism lecture notes
Some new material was added to the notes Tuesday at 9:15 pm.
|39) Wed. Apr 20||
Cancer as Disruption in Embryological Mechanisms; lecture notes
revised April 25, 11 am, to include links to videos shown in lectures
|40) Fri. Apr 22||Cancer, continued; additional notes on cancer treatment|
|41) Mon. Apr 25||Stem Cells; lecture notes|
|42) Wed. Apr 27||Evolutionary Developmental Biology; lecture notes|
review questions for the last part of the course:|
first set of review questions Modified slightly Friday at 8:20 pm
third set of review questions Modified Friday at 11 pm
Saturday 6 pm: NO MORE QUESTIONS WILL BE POSTED.
Dr. Harris will have office hours this week on Monday, Tuesday, and Wednesday beginning at about 11:00 am.
|FINAL EXAM: Thursday, May 5, at 8 AM|